Publications

2026

Papers in international journals

  1. D. Peeters, B. Obreja, N. Antonissen, Z. Saghir, U. Pastorino, M. Silva, G. de Bock, H. Gietema, F. Gleeson, M. Heuvelmans, S. Lam, G. Litjens, F. Mohamed Hoesein, C. Schaefer-Prokop, E. Scholten, A. Snoeckx, E. van der Heijden, R. Vliegenthart, M. Prokop, C. Jacobs and O. behalf of the Consortium, "Benchmarking of AI and Radiologists for Indeterminate Lung Nodule Malignancy Risk Estimation on Screening CT: The LUNA25 Challenge", Radiology: Artificial Intelligence, 2026.
    Abstract DOI PMID
  2. J. Twilt, A. Saha, J.S. Bosma, G. Giannarini, A. Padhani, D. Yakar, M. Elschot, J. Veltman, J. Fütterer, H. Huisman, M. de Rooij, F. the Consortium, A. Saha, J.S. Bosma, J. Twilt, B. van Ginneken, C. Noordman, I. Slootweg, C. Roest, S. Fransen, M. Sunoqrot, T. Bathen, D. Rouw, J. Immerzeel, J. Geerdink, C. van Run, M. Groeneveld, J. Meakin, D. Yakar, M. Elschot, J. Veltman, J. Fütterer, M. de Rooij, H. Huisman, A. Bjartell, A. Padhani, D. Bonekamp, G. Villeirs, G. Salomon, G. Giannarini, H. Huisman, J. Kalpathy-Cramer, J. Barentsz, K. Maier-Hein, M. Elschot, M. Rusu, N. Obuchowski, O. Rouviere, R. van den Bergh, V. Panebianco, V. Kasivisvanathan, A. Karagöz, A. Bône, A. Routier, A. Marcoux, C. Abi-Nader, C. Li, D. Feng, D. Alis, E. Karaarslan, E. Ahn, F. Nicolas, G. Sonn, I. Bhattacharya, J. Kim, J. Shi, H. Jahanandish, H. An, H. Kan, I. Oksuz, L. Qiao, M. Rohé, M. Yergin, M. Rusu, M. Khadra, M. Seker, M. Kartal, N. Debs, R. Fan, S. Saunders, S. Soerensen, S. Moroianu, S. Vesal, Y. Yuan, A. Malakoti-Fard, A. Mačiunien, A. Kawashima, A. Machadov, A. Moreira, A. Ponsiglione, A. Rappaport, A. Stanzione, A. Ciuvasovas, B. Turkbey, B. De Keyzer, B. Pedersen, B. Eijlers, C. Chen, C. Riccardo, D. Alis, E. Courrech Staal, F. Jäderling, F. Langkilde, G. Aringhieri, G. Brembilla, H. Son, H. Vanderlelij, H. Raat, I. Pikuniene, I. Macova, I. Schoots, I. Caglic, J. Zawaideh, J. Wallström, L. Bittencourt, M. Khurram, M. Choi, N. Takahashi, N. Tan, O. Rouvière, P. Franco, P. Gutierrez, P. Thimansson, P. Hanus, P. Puech, P. Rau, P. De Visschere, R. Guillaume, R. Cuocolo, R. Falcão, R. van Stiphout, R. Girometti, R. Briediene, R. Grigiene, S. Gitau, S. Withey, S. Ghai, T. Penzkofer, T. Barrett, V. Panebianco, V. Tammisetti, V. L\ogager , V. Černý, W. Venderink, Y. Law and Y. Lee, "Evaluating an AI-driven Triaging Workflow for MRI-based Clinically Significant Prostate Cancer Diagnosis: A Simulation Study", Radiology: Imaging Cancer, 2026;8.
    Abstract DOI PMID
  3. E. Munari, R. Polati, P. Antonini, D. Segala, L. Cima, A. Porcaro, A. Antonelli, R. Bertolo, G. Bogina, F. Tavora, A. Acosta, A. Caliò, K. Faryna, G. Litjens, G. Martignoni and M. Brunelli, "Atypical intraductal proliferation (AIP) of the prostate: a borderline lesion with important clinical implications", Precision Pathology, 2026;1:100004.
    DOI
  4. S. Jarkman, M. Lindvall, C. Lundström, D. Treanor and J. van der Laak, "Designing AI Tools for Pathology: A Mixed-Method Study on User Interface Design for Breast Cancer Lymph Node Metastases Detection", Intelligence-Based Medicine, 2026:100396.
    DOI
  5. M. Rijthoven, W. Aswolinskiy, L. Tessier, R. Salgado, J. van der Laak, F. Ciompi and TIGER consortium, "Analysis of computational tumor-infiltrating lymphocytes in breast cancer from the results of the TIGER challenge", Nature Communications, 2026.
    Abstract DOI
  6. G. Querzoli, G. Bogina, M. Marconi, N. Tumino, P. Vacca, L. Righi, S. Pilotto, A. Caliò, L. Cima, S. Gobbo, M. Cecchini, G. Paolino, F. Ciompi, R. Accolla, A. Scarpa, G. Lunardi, E. Marcenaro, L. Moretta, G. Zamboni and E. Munari, "HLA-G expression in non-small cell lung cancer: prognostic significance and interplay with PD-L1 and CD8+ tumor-infiltrating lymphocytes", Frontiers in Immunology, 2026;17.
    Abstract DOI
  7. A. Bouwmeester, T. Gootzen, M. Nobbenhuis, V. Rudaitis, C. van den Berg, H. van Beekhuizen, L. Alcalá, D. Smedts, N. Visser, V. Verhoef, T. Jonges, R. Zweemer, A. Leon-Catillo, C. Lems, J. de Hullu, J. van der Laak, M. Steenbeek and M. Simons, "Additional sectioning and AI -assisted diagnosis reveal underdiagnosis of serous (pre)malignancies in fallopian tube specimen from BRCA 1/2 carriers", Histopathology, 2026.
    Abstract DOI
  8. D. Schouten, J. van der Laak, D. Somford, H. Küsters-Vandevelde, N. Khalili and G. Litjens, "Three-dimensional reconstruction of gigapixel whole-mount histopathology specimens with RAPID", Scientific Reports, 2026.
    Abstract DOI
  9. N. Uysal, C. Grisi, K. Faryna, J. van Ipenburg and G. Litjens, "Towards patient-level Gleason grading from AI-based analysis of individual sections", Scientific Reports, 2026.
    Abstract DOI
  10. J. Dixon-Douglas, D. Drubay, R. Salgado, B. Acs, J. van der Laak, Y. Yuan, M. Amgad, L. Cooper, Y. Hagos, K. AbdulJabbar, J. Meakin, B. van Ginneken, H. Yan, J. Lemonnier, F. Penault-Llorca, M. Lacroix-Triki, H. Joensuu, P. Kellokumpu-Lehtinen, S. Loibl, C. Denkert, G. Viale, M. Colleoni, C. Sotiriou, M. Piccart, M. Dieci, S. Demaria, R. Kammler, A. Wolff, J. Sparano, S. Adams, S. Badve, R. Gray, G. Curigliano, A. Salomon, T. Nielsen, L. Pusztai, F. Ciompi, S. Michiels and S. Loi, "Artificial intelligence-based tumour infiltrating lymphocyte quantification in patients with triple-negative breast cancer: an independent validation study", The Lancet Oncology, 2026;27:1181-1192.
    DOI
  11. F. Khoraminia, M. Olislagers, F. de Jong, F. Akram, A. Nakauma Gonzalez, D. Lichtenberg, A. Stubbs, J. Costello, L. Rijstenberg, G. van Leenders, A. Vrieling, K. Aben, L. Kiemeney, R. Hoedemaeker, C. Bangma, S. Vermeulen, G. Litjens, N. Khalili and T. Zuiverloon, "Predicting bladder cancer molecular subtypes linked to bacillus Calmette-Guerin response from histology images using deep learning", Preprint, 2026.
    Abstract DOI
  12. J. Dixon-Douglas, D. Drubay, R. Salgado, B. Acs, J. van de Laark, Y. Yuan, M. Amgad, L. Cooper, Y. Hagos, K. AbdulJabbar, J. Meakin, B. Van Ginneken, H. Yan, J. Lemonnier, F. Penault-Llorca, M. Lacroix-Triki, H. Jounsuu, P. Kellokumpu-Lehtinen, S. Loibl, C. Denkert, G. Viale, M. Colleoni, C. Sotiriou, M. Piccart, M. Dieci, S. Demaria, R. Kammler, A. Wolff, S. Adams, S. Badve, R. Gray, G. Curigliano, A. Vincent-Salomon, T. Nielsen, L. Pusztai, F. Ciompi, S. Michiels and S. Loi, "Abstract PD11-02: Artificial Intelligence for Tumor-Infiltrating Lymphocytes in Early-Stage TNBC: Results of a Collaborative Prospective TIL Validation Challenge", Clinical Cancer Research, 2026;32:PD11-02-PD11-02.
    Abstract DOI
  13. E. Baumann, L. Schäfer, F. Meeuwsen, R. Kirsch, I. Nagtegaal, M. Berger, H. Dawson and I. Zlobec, "MSAI-Path: Predicting Microsatellite Instability From Routine Histology Slides Without Reinventing the Wheel", Modern Pathology, 2026;39(1):100932.
    Abstract DOI
  14. J. Spronck, L. van Eekelen, D. van Midden, J. Bogaerts, L. Tessier, V. Dechering, M. Demirel-Andishmand, G. de Souza, R. Nemeth, E. Munari, G. Bogina, I. Girolami, A. Eccher, B. Acs, C. Boyaci, N. Klubickova, M. Looijen-Salamon, S. Vos and F. Ciompi, "A tissue and cell-level annotated H&E and PD-L1 histopathology image dataset in non-small cell lung cancer", IEEE Journal of Biomedical and Health Informatics, 2026;():1-11.
    DOI
  15. E. Munari, P. Antonini, L. Cima, R. Polati, A. Caliò, S. Gobbo, M. Colecchia, G. Netto, A. Antonelli, R. Bertolo, C. Grisi, G. Litjens and M. Brunelli, "The evolution of prostate cancer grading: from Gleason score to risk taxonomy and the artificial intelligence revolution", Virchows Archiv, 2026.
    Abstract DOI
  16. K. Villiamsson, L. Fornstedt, G. Litjens, A. Amir, N. Sjöblom, A. Kaatonen, O. Vesala, F. Yacob, J. Paoli and N. Neittaanmäki, "Detection of basal cell carcinoma on whole-slide images from Mohs micrographic surgery using weakly supervised learning", JAAD International, 2026;28:76-85.
    DOI
  17. R. Spaans, N. Khalili, G. Litjens and J. van Basten, "Tussen potentie en praktijk: AI als motor voor zorgtransformatie bij prostaatkanker", Tijdschrift voor Urologie, 2026.
    Abstract DOI
  18. J. van der Zande, L. Alvarez-Florez, R. Volleberg, C. Brás, D. Karkalousos, R. Nijveldt, N. van Royen, T. Leiner, N. Khalili, G. Litjens, J. Thannhauser and I. Isgum, "Deep Learning for Cardiac Image Analysis", JACC: Cardiovascular Imaging, 2026.
    DOI

Preprints

  1. M. Stegeman, L. Philipp, F. van der Graaf, M. D'Amato, C. Grisi, L. Builtjes, J.S. Bosma, J. Lefkes, R. Weber, J. Meakin, T. Koopman, A. Mickan, M. Prokop, E. Smit, G. Litjens, J. van der Laak, B. van Ginneken, M. de Rooij, H. Huisman, C. Jacobs, F. Ciompi and A. Hering, "Designing UNICORN: a Unified Benchmark for Imaging in Computational Pathology, Radiology, and Natural Language", arXiv:2603.02790, 2026.
    Abstract DOI arXiv
  2. C. Grisi, K. Faryna, N. Uysal, V. Agosti, E. Munari, S. Kammerer-Jacquet, P. Salles, Y. Tolkach, R. Büttner, S. Semko, M. Pikul, A. Heidenreich, J. van der Laak and G. Litjens, "Deep Learning From Routine Histology Improves Risk Stratification for Biochemical Recurrence in Prostate Cancer", arXiv:2603.14187, 2026.
    Abstract DOI arXiv
  3. Q. Da, Y. Chen, M. Ju, Z. Ji, A. Zhou, W. Wang, M. Abikenari, P. Chikontwe, G. Larghero, B. Chen, P. Neidlinger, D. Zhong, S. Wang, W. Xu, D. Williamson, G. Corredor, S. Yang, L. Lu, X. Han, K. Yu, J. Huang, L. Barisoni, G. Litjens, A. Madabhushi, L. Zhu, C. Wang, J. Zhao and W. Hu, "Computational Pathology in the Era of Emerging Foundation and Agentic AI -- International Expert Perspectives on Clinical Integration and Translational Readiness", arXiv:2603.05884, 2026.
    Abstract DOI arXiv
  4. C. Lems, S. Moonemans, N. Klubíčková, B. Brattoli, T. Lee, S. Kim, V. Vilaplana, L. Pons, S. Hochman, M. Suárez-Franck, P. Fernandez, J. Drachneris, D. Petroska, R. Augulis, A. Laurinavicius, D. Oliveira, D. Montezuma, A. Bouwmeester, D. van Midden, A. Vos, S. Vos, J. van Ipenburg, M. Balkenhol, K. Winkler, I. Nagtegaal, K. Hebeda, U. Flucke, K. Grünberg, J. Skopal, B. Chohan, J. Temprana-Salvador, E. Munari, L. Cima, G. Querzoli, Y. Belisario, J. Faber, G. van Leenders, J. von der Thüsen, L. Brosens, R. de Krijger, P. Wesseling, S. Florquin, M. Maniewski, A. Kowalewski, R. Barna, D. Tiniakos, J. Gros, R. Donders, J. Maurits, M. Lu, C. Chen, F. Mahmood, J. van der Laak, N. Khalili, F. Meeuwsen and F. Ciompi, "DALPHIN: Benchmarking Digital Pathology AI Copilots Against Pathologists on an Open Multicentric Dataset", arXiv:2605.03544, 2026.
    Abstract DOI arXiv
  5. S. Moonemans, S. Ram, F. Meeuwsen, C. Lems, J. van der Laak, G. Litjens and F. Ciompi, "Democratising Pathology Co-Pilots: An Open Pipeline and Dataset for Whole-Slide Vision-Language Modelling", arXiv:2512.17326, 2026.
    arXiv
  6. C. Grisi, J. van der Laak and G. Litjens, "A Distributional Robustness Margin For Pathology Foundation Models", arXiv:2607.25497, 2026.
    Abstract DOI arXiv

Papers in conference proceedings

  1. J. Dusseljee, S. de Boer and A. Hering, "Kidney Cancer Detection Using 3D-based Latent Diffusion Models", Bildverarbeitung für die Medizin 2026, 2026:411-418.
    Abstract
  2. A. Arab, V. Garcia, S. Kahaki, M. van Rijthoven, R. Salgado, B. Gallas, F. Ciompi, N. Petrick and W. Chen, "Assessment of AI segmentation models in histopathology whole slide images: the effect of the unit of analysis", Medical Imaging 2026: Digital and Computational Pathology, 2026:31.
    DOI

PhD theses

  1. P. Venditelli, "Learning from histopathology images: AI-driven biomarkers for pancreatic ductal adenocarcinoma", PhD thesis, 2026.
    Abstract Url