Papers in international journals

  1. R. Remark, T. Merghoub, N. Grabe, G. Litjens, D. Damotte, J. Wolchok, M. Merad and S. Gnjatic, "In-depth tissue profiling using multiplexed immunohistochemical consecutive staining on single slide", Science Immunology, 2016;1(1):aaf6925-aaf6925.
    Abstract DOI PMID Cited by ~139
  2. F. Ciompi, S. Balocco, J. Rigla, X. Carrillo, J. Mauri and P. Radeva, "Computer-aided detection of intracoronary stent in intravascular ultrasound sequences", Medical Physics, 2016;43(10):5616.
    Abstract DOI PMID Cited by ~16
  3. O. Debats, A. Fortuin, H. Meijer, T. Hambrock, G. Litjens, J. Barentsz and H. Huisman, "Intranodal signal suppression in pelvic MR lymphography of prostate cancer patients: a quantitative comparison of ferumoxtran-10 and ferumoxytol", PeerJ, 2016;4:e2471.
    Abstract DOI PMID Download Cited by ~7
  4. O. Debats, M. Meijs, G. Litjens and H. Huisman, "Automated multistructure atlas-assisted detection of lymph nodes using pelvic MR lymphography in prostate cancer patients", Medical Physics, 2016;43(6):3132.
    Abstract DOI PMID Download Cited by ~2
  5. G. Litjens, C. Sánchez, N. Timofeeva, M. Hermsen, I. Nagtegaal, I. Kovacs, C. Hulsbergen-van de Kaa, P. Bult, B. van Ginneken and J. van der Laak, "Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis", Scientific Reports, 2016;6:26286.
    Abstract DOI PMID Cited by ~836
  6. B. Bejnordi, M. Balkenhol, G. Litjens, R. Holland, P. Bult, N. Karssemeijer and J. van der Laak, "Automated Detection of DCIS in Whole-Slide H&E Stained Breast Histopathology Images", IEEE Transactions on Medical Imaging, 2016;35(9):2141-2150.
    Abstract DOI PMID Cited by ~83
  7. B. Nijhof, A. Castells-Nobau, L. Wolf, J. Scheffer-de Gooyert, I. Monedero, L. Torroja, L. Coromina, J. van der Laak and A. Schenck, "A New Fiji-Based Algorithm That Systematically Quantifies Nine Synaptic Parameters Provides Insights into Drosophila NMJ Morphometry", PLOS Computational Biology, 2016;12:e1004823.
    Abstract DOI PMID Cited by ~62
  8. A. Setio, F. Ciompi, G. Litjens, P. Gerke, C. Jacobs, S. van Riel, M. Wille, M. Naqibullah, C. Sánchez and B. van Ginneken, "Pulmonary nodule detection in CT images: false positive reduction using multi-view convolutional networks", IEEE Transactions on Medical Imaging, 2016;35(5):1160-1169.
    Abstract DOI PMID Download Cited by ~997
  9. J. Charbonnier, M. Brink, F. Ciompi, E. Scholten, C. Schaefer-Prokop and E. van Rikxoort, "Automatic Pulmonary Artery-Vein Separation and Classification in Computed Tomography Using Tree Partitioning and Peripheral Vessel Matching", IEEE Transactions on Medical Imaging, 2016:882-892.
    Abstract DOI PMID Cited by ~53
  10. T. Kobus, J. van der Laak, M. Maas, T. Hambrock, C. Bruggink, C. Hulsbergen-van de Kaa, T. Scheenen and A. Heerschap, "Contribution of Histopathologic Tissue Composition to Quantitative MR Spectroscopy and Diffusion-weighted Imaging of the Prostate", Radiology, 2016;278(3):801-811.
    Abstract DOI PMID Download Cited by ~31
  11. B. Bejnordi, G. Litjens, N. Timofeeva, I. Otte-Holler, A. Homeyer, N. Karssemeijer and J. van der Laak, "Stain specific standardization of whole-slide histopathological images", IEEE Transactions on Medical Imaging, 2016;35(2):404-415.
    Abstract DOI PMID Cited by ~250
  12. G. Litjens, R. Elliott, N. Shih, M. Feldman, T. Kobus, C. Hulsbergen-van de Kaa, J. Barentsz, H. Huisman and A. Madabhushi, "Computer-extracted Features Can Distinguish Noncancerous Confounding Disease from Prostatic Adenocarcinoma at Multiparametric MR Imaging.", Radiology, 2016;278(1):135-145.
    Abstract DOI PMID Cited by ~52

Papers in conference proceedings

  1. N. Lessmann, I. Išgum, A. Setio, B. de Vos, F. Ciompi, P. de Jong, M. Oudkerk, W. Mali, M. Viergever and B. van Ginneken, "Deep convolutional neural networks for automatic coronary calcium scoring in a screening study with low-dose chest CT", Medical Imaging, 2016;9785:978511-1 - 978511-6.
    Abstract DOI Cited by ~47
  2. H. Kost, A. Homeyer, P. Bult, M. Balkenhol, J. van der Laak and H. Hahn, "A generic nuclei detection method for histopathological breast images", SPIE Proceedings, 2016.
    Abstract DOI Cited by ~4
  3. G. Litjens, K. Safferling and N. Grabe, "Automated robust registration of grossly misregistered whole-slide images with varying stains", Medical Imaging, 2016;9791:979103.
    Abstract DOI
  4. T. Mertzanidou, J. Hipwell, S. Reis, B. Bejnordi, M. Hermsen, M. Dalmis, S. Vreemann, B. Platel, J. van der Laak, N. Karssemeijer, R. Mann, P. Bult and D. Hawkes, "Whole Mastectomy Volume Reconstruction from 2D Radiographs and Its Mapping to Histology", Breast Imaging, 2016;9699:367-374.
    Abstract DOI Cited by ~4


  1. F. Ciompi, K. Chung, A. Setio, S. van Riel, E. Scholten, P. Gerke, C. Jacobs, U. Pastorino, A. Marchiano, M. Wille, M. Prokop and B. van Ginneken, "Pulmonary nodule type classification with convolutional networks", Medical Image Computing and Computer-Assisted Intervention, 2016.
  2. M. Hermsen and J. van der Laak, "Highly multiplexed immunofluorescence using spectral imaging", DPA's Pathology Visions Conference 2016, San Diego, CA, US, 2016.