We propose a novel framework for controllable pathological image synthesis for data augmentation. Inspired by CycleGAN, we perform cycle-consistent image-to-image translation between two domains: healthy and pathological. Guided by a semantic mask, an adversarially trained generator synthesizes pathology on a healthy image in the specified location. We demonstrate our approach on an institutional dataset of cerebral microbleeds in traumatic brain injury patients. We utilize synthetic images generated with our method for data augmentation in cerebral microbleeds detection. Enriching the training dataset with synthetic images exhibits the potential to increase detection performance for cerebral microbleeds in traumatic brain injury patients.
Adversarial cycle-consistent synthesis of cerebral microbleeds for data augmentation
K. Faryna, K. Koschmieder, M. Paul, T. van den Heuvel, A. van der Eerden, R. Manniesing and B. van Ginneken
Medical Imaging Meets NeurIPS Workshop - 34th Conference on Neural Information Processing Systems (NeurIPS) 2020.